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Elizaveta D. Belyaeva, Natalia V. Komarova, Alexander E. Kuznetsov
Protein engineering of lactate oxidase
Abstract
Abstract. Lactate oxidase (EC 1.1.3.2) has
substantial practical importance as an enzyme extensively used in medical
diagnostics and the food sector for detection of L–lactate. This study provides
a comprehensive summary of the outcomes obtained from protein engineering
studies conducted on lactate oxidases. The primary objectives of these
investigations were to elucidate the underlying mechanism of action of the
enzyme and enhance its operational features.
Key words: lactate oxidase, enzymes, lactate,
diagnostics, mutations
Copyright (C) Chemistry Dept., Moscow State University, 2002
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